I was born in the sixties, and in my lifetime there have been so many advances.  In a couple of generations, the changes that have occurred on the earth, environmentally, industrially, socially, chemically and technologically have been vast.   We have to adapt to these changes, and that takes time, many centuries even, but do people really stop to take any of this into consideration when looking at why our health is failing?

  • Before Edison invented the first commercially viable light bulb we had relied on candles and then gas light. Electric light enabled people to work longer hours and factories began to run night shifts.  
  • As people flocked to the cities in the industrial heartlands a way to feed them had to be found – and so began the industrialisation of our food supply. Then the arrival of the superstore chains brought food preservation technologies, and high efficiency global logistics.   Most of our food had been grown and consumed locally, and there were recognized seasonal variations in our diet.  We all love the convenience, however we also need to recognize the wide ranging problems this brings.  People are now fighting back with rising calls to buy and eat local.
  • If you are 40 years old you can probably remember when there were just three channels, BBC1, BBC2 and ITV. Channel 4 didn’t arrive on the scene until 1982. Retune your Smart TV now and it will pick up hundreds of channels. They all compete for your attention and lure you to sit there for hours.
  • It wasn’t until the mid-nineties that the Internet started to become widely available. Now there is literally the whole knowledge of mankind available at your fingertips. Unfortunately, there is also a vast army of people dedicated to generating “click bait” and weapons of mass distraction like YouTube, Facebook, Twitter and Instagram – to name just a few.
  • There are gyms springing up all over the place and there are any number of fitness gurus to follow online – yet we have seen a dramatic decrease in the amount of physical exercise people take. Sitting is being called the new smoking and we have more illnesses due to our sedentary life styles than ever before.  
  • In the Internet Age we can now work from home, and order our food to our front door. Some people hardly go outside their front door.   It is now possible to create a life where we never have any meaningful social interaction.  We thought the arrival of the Japanese Bedroom Boy was weird, but now around the world there are huge numbers of people who no longer actually meet people in real life.  In 2003 California-based Linden Labs brought out Second Life, a virtual online world. Ten years later there were over a million regular users living in there! And now what your kids really want for their birthday is one of the VR virtual reality headsets!

This modern epidemic of chronic illness, once thought to be exclusively a “first world problem” is rapidly spreading to the developing nations.  We have lost touch with the outside world, with nature and the elements that support us.  People do not go for walks, spend time outside or gather knowledge from our elders, valuing and cherishing them.  Instead we send our elders away into care homes and our family and social structure has become so fractured and dysfunctional. 

The question needs to be asked as to why do we have these sky rocketing chronic illnesses with adults and children in the last 40-50 years.  So what has changed to make us sicker, quicker?                                                                                                    

The experts in epidemiology are confirming that life expectancy is no longer increasing, it is levelling out and in some countries decreasing worryingly.  Many people today could actually outlive their own children. We have a crisis coming and we need to make changes to avert this.

We have such amazing resources available to us, yet we are the sickest humans that have ever been.

Go back a couple of generations and people felt that disease was a matter of bad luck, or punishment from God. More recently there has been a trend to blaming it upon our genes.  People believe that they are destined to live a life of chronic disease, because their parents had heart problems, or Alzheimer’s runs in the family, or women in our family are prone to breast cancer – you hear this all the time. 

We have a health system that achieves near miraculous results when dealing with trauma and acute problems, but it fails miserably when it comes to the chronic problems.

There has to be a change!  People need to wake up, get the information they need and start taking responsibility for their most wonderful possession, their Body.  Sadly, many just treat it like some comfy “onesie” that their moist-robot or flesh-puppet can loaf around in all day.  For many, focused on their outer world; they invest more thought and care for their clothes and appearance than they do for their bodies.

In this technologically advanced Information Age, we have come to look at our bodies as highly complex machines, made up of a vast number of different parts and processes.  If we have digestion problems, we go to a specialist in that – a gastroenterologist, to run lots of tests and imaging.  But perhaps to arrive at the answer we need to look much closer to home and ask ourselves why we might have gut issues.  Could the answer come from our food, our gut flora, our levels of cellular toxicity or our nutritional deficiencies?

When faced with a variety of different options and an overload of often conflicting advice, our brains go to our default.  What is everyone else doing? – I’ll do that too.  I’ll look it up online to find the latest answers. But maybe the problem with this is, that although our lives are changing so fast – the human body has not yet evolved to deal with these challenges

So what is Ageing?

This is a question that can be answered in so many ways.  Positively it can be seen as the passage of life, the accumulation of wisdom, and meaningful human experience.  But, as time passes, we are forced to focus on the physiological and chemical changes in the body.   The body becomes stiff – there is a lack of flow, the body becomes stagnant and rigid.  This is a result of a loss of cells and their inability to adapt to the environment around us.  The health of your cells pretty much determines the health of you.  We need to look at the way the human body can sustain itself, despite the challenges we place on ourselves. How do we continue to adapt and regenerate, whilst walking the persistent road to getting older and closer to death?

As you age and deteriorate you enter a catabolic state, instead of the body renewing and regenerating at a healthy rate, the mitochondria no longer has the same power and the body starts to break down.  You can’t produce the same energy and your rate of cell division diminishes.  Therefore, you become more prone to disease and more susceptible to inflammation as these processes take place.

Mitochondria, the power plants of every cell in your body, are now regarded as the most upstream system for tackling these issues.  In ageing, certain organs tend to go first, the heart the lungs, the brain, the kidneys the endocrine organs and muscles as they have a very high energy demand, but very low energy reserves.

Mitochondria not only produce energy for you, but are also responsible for creating things called ROS Reactive Oxygen Species.   These signal to the molecules how much energy needs to be produced, and they also signal cell death. So ROS play a very significant role in our health and wellbeing and are regarded as very important molecules.

We should be asking ourselves daily: are we doing things that actually stimulate our mitochondria, and encourage our cells to build up their own anti-oxidant defense system?

We keep being reminded to reduce and minimise our stress wherever we can.  However, when you place a human, a child, cat, dog or even a plant into a completely stress free environment they do not actually thrive.  Even with plants, whether it is the lack of sunlight or water, it is actually that stress that alerts our body that it needs something.  It may be very tough initially, but that triggers the increase of anti-oxidants in your immune system to wherever it is called for.  So, by testing your resilience, you can encourage your body to become stronger and healthier.

Take the inflammatory response – it is only intended for acute situations.  However, when it is there chronically it can set up metabolic diseases such as diabetes and even cancers.  Since the 1990s research has been showing that most diseases can be traced back to an alteration in, or insufficiency of, mitochondria.  Mitochondrial DNA, when mutated, is the base for mitochondrial disease.  The number of mutated DNA has to reach a certain level before we start to see clinical symptoms.  This very much depends on the energy demand of the tissue.   If a particular tissue’s job is to produce insulin and there is not enough power to do this then it can be a precursor to diabetes.  If the major function of that tissue is cognitive function and we do not have enough mitochondria to do this, then you cannot think properly anymore.  Or the major task is to get up out of a chair, stand up and walk around, but the muscles do not have enough mitochondria then you cannot perform even that basic task.

The more mutations there are, the greater the mitochondrial loss and the more severe the symptoms tend to be in that tissue area.  Everyone over 40 experiences a mitochondrial decline. This means we make less energy than we did when we were young, and half of us over 40 are already starting to experience the onset of mitochondrial deficiency. 

When the body is weakened from a lack of hermetic stress then it is unlikely to thrive.  Hormesis is the process of conditioning and adaptation in which low levels of stress stimulate cellular and molecular pathways that improve the capacity of cells and organisms to withstand greater stress.  When cells are not exposed to hormetic stress they atrophy, they weaken, and they lose their capacity to produce energy.  When that happens they lose their resiliency in the face of stress, which in turn means you start to see symptoms, diseases and accelerated cell death.  You also become susceptible to all these types of stressors in the environment, the infections, sleep deprivation, toxins and many others.  Those stressors can now tip your balance into cell danger response mode.  This cell danger response mode is the mitochondria protecting the cell.  Mitochondria are now being seen as the primary cellular defence against viruses, bacteria and toxins, alerting neighboring cells to the danger.  The cell danger response signal, causes the mitochondria to shut down its basic functions as a protective mechanism.  The problem with this is, if it doesn’t turn back on once the threat is resolved, this can lead to the dysfunction of the cell and the mitochondria.  It has now become more widely accepted that many chronic diseases are very much linked to cell danger response.


So what can be done?

The dipeptide carnosine was discovered just over 100 years ago by the Russian chemist Vladimir Guleyvich.  It was used for many therapeutic purposes in Russian medicine from that time, with some extraordinary results.  It should not come as a surprise therefore that these properties of carnosine would be useful in preserving the health of cosmonauts during the rigors of long endurance space flight.

Today we have Karnozin Extra, a highly potentized formulation of carnosine targeted at supporting the mitochondria, enabling it to adapt to the stresses of our modern day lives.  It has the greatest capacity to reduce hydroxy radicals, to repair receptor damage and encourages a much greater production of ATP, which we in turn, use to power the body and help us to regenerate.

Most illness arises through a lack of mitochondria, a lack of power in the body to regenerate and repair itself.  So instead of treating symptoms, we must address the lack of power in the body.  The body will always favour heart rate and respiration first.  Any surplus power will go to the next priority, the endocrine system, methylation and digestion – whatever has the greatest demand.  This is the new paradigm to living and experiencing greater health and wellness.  It is about having enough power for the body to keep regenerating itself effectively, so we can keep living our lives to the fullest and enjoying a great quality of life.

The supplements and protocols from Mitochondrial Rescue LLC can help provide you with this protection and support, to restore the body’s mitochondria to their full potential and slow down the ageing process.

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